Embark on a groundbreaking journey into the complexities of cardiometabolic diseases, delving into adipocyte remodeling, insulin resistance, and lipolysis dysfunction. Simultaneously, screen the latest anti-obesity drugs with our cutting-edge 3D BioSol™ AT Obesity Platform. This avant-garde tool is not just a platform; it's the cornerstone for unraveling the pathophysiology of cardiometabolic diseases. It goes beyond by assessing the cardiotoxicity and hepatotoxicity of drugs through our state-of-the-art 3D BioSol™ Heart and Liver models.
Driven by innovative 3D cell-based technology, this platform presents customizable 3D adipose tissue models meticulously crafted from diverse depots like visceral, subcutaneous, and breast. Augmenting its capabilities are human pluripotent stem cell-derived cardiac and hepatic spheroids and organoids, elevating your research to unprecedented levels.
Embark on a transformative journey with 3D BioSol™ AT Chemically-induced Obesity Organoids (CIOO), a pioneering amalgamation of 3D BioSolTM AT derived from healthy human donor cells (primary SVF of the adipose tissue). Through our proprietary methods, media kit, and expertly crafted cocktails, this powerful model induces progressive adipose tissue (AT) dysfunction, encompassing insulin resistance, adipocyte hypertrophy, and fibrosis.
Commence on a new era of research, unlocking the potential of 3D BioSol™ AT Chemically-induced Obesity Organoids (CIOO) for a deeper understanding of adipose tissue dysfunction and advancing drug development.
Immerse yourself in the unique capabilities of 3D BioSol™ AT PDOO, featuring 96- or 384-well plates housing mini-organs derived from human patients with BMIs ranging from 30 to 60, along with healthy controls at BMIs of 25-27. Unparalleled in the market, this platform provides unmatched versatility.
Customize your plates to perfection by specifying the number of patients and BMI ranges, creating unique mixes with diverse patient cells. Backed by meticulously documented patient histories, encompassing details like gender, race, and prevalent diseases, our model offers an ideal framework for assessing compound effects while considering crucial population characteristics.
Unlock tailored insights and elevate your research with 3D BioSol™ AT PDOO—where versatility meets precision.
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